Jeremy Kleberg
Biochemistry and Molecular Biology Student at the University of Florida
About Me
Jeremy is a dedicated, hard-working student whose work has prepared him for application into medical school.At the University of Florida, Jeremy is involved in various scientific and educational involvements that are working to prepare him for matriculation into medical school. Through his work with Phi Delta Epsilon pre-medical fraternity, physician shadowing, and position at UF Health Shands, he has been able to experience the healthcare field. Furthermore, he has continued his scientific inquiry through his research in the Zhang and Kolb lab related to developing potential cancer therapeutics. Additionally, with hopes of going into medical education, he has sought involvement with First yEar Florida, Preview Staff, and Student Admissions Officers to gain a working understanding of the higher education field.
Research
Jeremy has been working with Dr. Ryan Kolb in the University of Florida Department of Pathology, Immunology, and Laboratory Medicine on a project titled "ANGPTL4 as a potential therapeutic target for clear cell renal carcinoma" since May of 2022. Through this I have developed new skills while aiding in this project. Through learning cell culture techniques, flow cytometry, animal models, and many more advanced techniques, I have been able to aid in the progression of this project. Through the investigation, we have made discoveries that have been published in Cancer Communications Journal and are working on underlying other effects of this molecule. Specifically, we want to uncover how ANPTL4 promotes angiogenesis and how this discovery could possess therapeutic potential for clear cell renal carcinoma patients. To complete the rest of the project, I will analyze receptors that trigger the expression of this molecule and decrease the receptors expression to see its effect on ANPTL4 expression and overall tumor growth. Through continued animal studies and cellular experiments, we will hopefully uncover how ANGPTL4 targeting can be a potential therapeutic.
Coursework
As a Biochemistry and Molecular Biology student, I have had the opportunity to develop knowledge that aids in the understanding and progression of my research endeavors. Additionally, through courses related to my Education Studies minor, I have developed educational skills that help me in presenting knowledge to my peers. The following courses are some that I would like to highlight:BCH4024: Introduction to Biochemistry and Molecular Biology
CHM4300L: Biochemistry and Molecular Biology Lab
MCB3020: Basic Biology of Microorganisms
CHM3120: Introduction to Analytical Chemistry
BCH5413: Mammalian Molecular Biology and Genetics
PCB3063: Genetics
EEX3093: Exceptional People in School and Society
EDF4430: Measurement and Evaluation in Education
Cirriclulm Viate
A downloadable copy of my Cirriclum Vitae can be found below as well as some highlighted sections.
Teaching Experience
Through being a First Year Florida Peer Leader, I have taught, along with a University of Florida Faculty, a one credit class titled SLS1102. Through this class which I have taught three times, I have helped first year students at the University of Florida get acclimated to the university and educate them on all of the opportunities and resources available. Additionally, I have been a teaching assistant for MCB3020: Basic Biology of Microorganisms and BCH2911: Science for Life. Through these classes, I have helped students in understanding course material and have helped them in understanding the vast amount of research available at the University of Florida, respectively. I have been a teaching assistant for MCB3020 for three semesters and a teaching assistant for BCH2911 for two semesters.
Publications
Through my work in the Zhang and Kolb lab, I have had the opportunity to get my research published. I have published a paper in Cancer Research Communications Journal with a paper titled "ANGPTL4 suppresses clear cell renal cell carcinoma via inhibition of lysosomal acid lipase". The citation of the paper is as follows: Jin Z, De U, Tithi TI, Kleberg J, Nataraj A, Jolley E, Carelock ME, Davies BS, Zhang W, Kolb R. ANGPTL4 suppresses clear cell renal cell carcinoma via inhibition of lysosomal acid lipase. Cancer Res Commun. 2024 Aug 6. doi: 10.1158/2767-9764.CRC-24-0016. Epub ahead of print. PMID: 39105498.